A NEW APPROACH FOR SPLIT RENAL FUNCTION EVALUATION OF GLOMERULAR FILTRATION RATE, PERFUSION AND PLASMA FLOW BY NUMERICAL ANALYSIS OF 3D MSCT-BASED MODELS

Alyaev Yu.G.1, Khokhlachev S.B.2, Fiev D.N.1, Borisov V.V.1, Proskura A.V.1, Iurova M.V.1

Introduction. Instrumental methods of examination may alter the course of treatment and patients’ management. Several studies have shown that interobserver variability in values obtained with renal scintigraphy (RS) can be as high as 10%, however, RS remains the standard investigation for the assessment of split renal function. Objective. This paper aims to present how numerical analysis of abdominal MSCT results can be used to evaluate split renal function. Materials and methods. A prospective study was launched in a Research Institute for Uronephrology and Reproductive Health from November, 2015 to May, 2017. 88 patients were enrolled into the study (2 with hydronephrosis, 10 with hypertensive kidney disease, 5 with stone kidney disease, 2 with kidney anomalies, 69 with renal tumors). Comparison made between renal scintigraphy data and 3D MSCT-based models. Results. CT-based methods for the calculation of split renal function with 3D-models showed correlation with renal scintigraphy (p<0.004). Conclusion. A new approach for split kidney function assessment based on contrast-enhanced CT with 3D-models and mathematical analysis allows for both acquiring detailed data on clinical anatomy and evaluation of renal function to promote preoperative decision-making. It showed strong correlation with no significant difference in comparison with RS in terms of glomerular filtration rate, perfusion and plasma flow.

1 - I.M. Sechenov First Moscow State Medical University (Sechenov University), 2 - Central Scientific and Research Institute for Dentistry. Моscow, Russia.

 

Keywords:3D-models, MSCT, scintigraphy, split renal function assessment.

 

 

Corresponding author:

Iurova M.V., Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript .

 

 

For citation: Alyaev Yu.G., Khokhlachev S.B., Fiev D.N., Borisov V.V., Proskura A.V., Iurova M.V. A new approach for split renal function evaluation of glomerular filtration rate, perfusion and plas-ma flow by numerical analysis of 3D MSCT-based models. REJR 2018; 8(2):105-109. DOI:10.21569/2222-7415-2018-8-2-105-109.

Received: 23.03.2018 Accepted: 16.05.2018