Purpose. To determine the diagnostic efficiency of methods of complex radiological diagnosis (OPG, conventional radiography, MSCT, CBCT) in the evaluation of osteonecrosis in patients on preoperative stage.

Materials and methods. The study included 108 (100%) drug-dependent patients with a diagnosis of «Toxic phosphorus osteonecrosis of the facial bones». 7-14 days after surgical treatment, 71 patients (65,7%) underwent radiological examination (radiography, OPG, MSCT). CBCT was performed in 59 patients (54,6%). Part of the patients were subsequently subjected to complex radiological examinations at the various postoperative stages: after 1-1,5 months, 3-4 months, 5-6 months, 1-1,5 years, after 2 years or more. These stages also included radionuclide research (SPECT, scintigraphy). The complex of radiological methods in patients with desomorphine addiction at the postoperative stages of treatment was carried out to evaluate surgical intervention and to plan further management of this group of patients.

Results. Тhe diagnostic efficiency parameters at the postoperative stage for MSCT were: the sensitivity – 98,1%, the specificity – 99,6%, the accuracy – 98,8%, for CBCT were: the sensitivity – 98,1%, the specificity – 99,6%, the accuracy – 98,8%, for orthopantomography: the sensitivity – 76,3%, the specificity – 76,0%, the accuracy – 76,1%, for skull x-ray: the sensitivity – 59,8%, the specificity – 57,9%, the accuracy – 59,4%.

Conclusions. Thus, the application of complex highly informative radiological methods (MSCT, CBCT, radionuclide diagnostics) in desomorphine dependence patients at the postoperative stages of treatment allows correctly evaluating the performed surgical treatment, also enables to timely identify the possible spread of pathological changes to the intact structures of the facial (brain) parts of the skull, and  to evaluate the lower jaw prosthetics.