The role of ultrasound and laboratory methods of studying comorbid conditions in parakinson’s disease.

Bayborodina I.V., Zavadovskaya V.D., Zhukova N.G., Fetisova T.V., Yazhinova V.N., Danilenko A.V., Basanova A.V., Zangeeva L.A.

Purpose. To study the effect of certain parameters of atherogenesis on the clinical manifestations of Parkinson's disease. Material and methods. A total of 84 patients were examined: 32 of them with BP and 52 without clinical signs of BP (comparison group). A method of duplex scanning of the extra-cranial region of the brachiocephalic arteries was applied using a Toshiba 500 ultrasound scanner using a linear sensor with a frequency of 12 MHz (Toshiba Aplio - 2010). Results. As a result of this work, indicators were obtained indicating a lower level of total cholesterol and its fractions, as well as lower values of CMM thickness at the level of the bifurcation of the carotid arteries with a more rare occurrence of atherosclerotic plaques in the lumen of the vessels in the main group, unlike the comparison group. A direct correla-tion was established between the thickness of the CMI of the carotid arteries at the level of bifurcation on both sides, as well as between the level of LDL cholesterol and total cholester-ol. Analysis of lipid metabolism and intima-media complex thickness in patients with varying degrees of severity of Parkinson's disease on the Hen-Yar scale revealed a statistical-ly significant relationship between total cholesterol in the blood of patients with PD and the degree of motor manifestations of the Henn Yar scale. The maximum concentration of total cholesterol is noted in the mixed (acido-rigid-shivering) form of BP. Conclusion. Thus, the results of ultrasound and laboratory studies indicate a de-crease in atherogenesis in Parkinson's disease, which suggests a decrease in the risk of ath-erosclerosis in this cohort of patients.
1- LLC CDC "RITM". Republic of Buryatia, Ulan-Ude, Russia. 2 - Siberian State Medical University. Tomsk, Russia.



 

Keywords: parkinson's disease, duplex scanning of the extracranial part of brachiocephalic arteries, atherosclerosis, thickness of intima-media.

 

Corresponding author:Bayborodina I.V., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript .

 

or citation: Bayborodina I.V., Zavadovskaya V.D., Zhukova N.G., Fetisova T.V., Yazhinova V.N., Danilenko A.V., Basanova A.V., Zangeeva L.A. The role of ultrasound and la-boratory methods of studying comorbid conditions in parakinson’s disease. REJR 2018; 8 (4):23-33. DOI:10.21569/2222-7415-2018-8-4-23-33.

Received:15.10.18Accepted:29.10.18