Contrast-enhanced mri of the heart in detection and quantification of borderline myocardial damage within hypertrophic cardiomyopathy.
Mochula O.V., Tereshenkova E.K., Pavljukova E.N., Ussov W.Yu.
Purpose. To evaluate the mode of possible relationship between left ventricular (LV) hypertrophy and hidden myocardial damage, as well as the threshold of forming LV myocardial damage in the absence of a coronary arteries critical stenosis. |
Cardiology Research Institute. Tomsk National Research Medical Centre, Russian Academy of Sciences. Tomsk, Russia. |
Materials and methods. Contrast-enhanced MRI of the heart was carried out in 16 patients with hypertrophic cardiomyopathy (HCM). Anatomic thickness in every segment of left ventricle was assessed with submillimeter preciseness, and related to the presence or absence of contrast uptake to myocardial wall in the segments, as MRI sign of myocardial damage. Results. When plotting the thickness of the left ventricular wall against the uptake of the paramagnetic contrast it was found that when the thickness of the interventricular sep-tum is over 12 mm the probability of observing the pathologic accumulation of contrast agents to the region is 0.44; the anterior wall borderline thickness is over 11 mm, with re-spective probability 0.51; and in the lateral wall - more than 13 mm delivered the contrast uptake to myocardium with the probability 0.47. Conclusion. In patients with hypertrophic cardiomyopathy, there is a borderline threshold relationship between left ventricular myocardial hypertrophy and intersegmental contrast uptake, as a symptom of latent myocardial damage.
Keywords:cardiac MRI, paramagnetic contrast enhancement, hypertrophic cardiomyopathy, myocardial hypertrophy.
Corresponding author:Amiryan A.G., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript
For citation: : Mochula O.V., Tereshenkova E.K., Pavljukova E.N., Ussov W.Yu. Contrast-enhanced mri of the heart in detection and quantification of borderline myocardial damage within hypertrophic cardiomyopathy. REJR 2017; 7 (2):46-55. DOI:10.21569/2222-7415-2017-7-2-46-55./em>
Received: 15.04.2017 Accepted:20.05.2017