8.2.12

THE ROLE OF THE SPLIT RENAL FUNCTION CALCULATION (GLOMERULAR FILTRATION RATE), BASED ON 3D MSCT- MODELS OF KIDNEY WITH UROLITHIASIS

Iurova M.V.

Some pathologic processes compromise renal function and as result worsen glomerular filtra-tion rate (GFR). The CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equa-tion was developed in an effort to create a more correct formula to estimate GFR, however, it is not able to assess split renal function. Objective. This paper aims to present how numerical analysis of abdominal multi-spiral computed tomography (MSCT) results correlate with data of CKD-EPI equation. Materials and methods. In this Institutional prospective cohort study, MSCT scans of 16 patients undergoing multiphasic renal protocol with 3D-reconstruction and numerical estimation were reviewed. Comparison was made by means of Pearson coefficient and Youden index. Results. MSCT-based methods for the calculation of split renal function with 3D-models showed strong correlation with CKD-EPI (p<0.001). Conclusion. Data received using the 3D-MSCT in comparison with CKD-EPI equa-tion are equally accurate with low bias in GFR-assessment. However new approach has great advantages, because allows for both acquiring detailed data on clinical anatomy and evaluation of renal function, that made it not only precise but also more informative for de-cision-making in clinical practice. Such application of high-tech imaging method applied to the field of radiology may alter the course of patients’ management when pathologic process is just beginning to correct premorbid conditions.

I.M. Sechenov First Moscow State Medical University (Sechenov University). Моscow, Russia.


 

Keywords: 3D-models, CKD-EPI, glomerular filtration rate, MSCT, split renal function assessment.

 

 

Corresponding author:

Iurova M.V., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

 

For citation: Iurova M.V. The role of the split renal functions calculation (glomerular fil-tration rate), based on 3D MSCT-models of kidney with urolithiasis. REJR 2018; 8 (2):116-122. DOI:10.21569/2222-7415-2018-8-2-116-122.

Received: 23.03.2018 Accepted: 18.05.2018