The expert system for computer-aided analysis of osteoscintigrams with visual assessment of image quality

The possibilities of using computed tomography heart- axis-oriented multiplanar reformations in diagnostics of pulmonary artery atresia

Burkov S.M., Kosyh N.J., Savin S. Z., Sviridov N.M.

Purpose. The aim of the work is to build an expert system for computer-aided analysis of skel-eton scintigramms with visualization of medical image quality assessment. Materials and methods. Metastatic lesion of the skeleton is one of the most frequent tumor. The planar osteoscintigramms of the skeleton of patients who are in complete remis-sion and in the phase of progression of the disease with metastases to the skeleton were studied by means of computer-aided analysis. For this purpose, an expert system was devel-oped for the analysis of planar scintigraphic images of the human skeleton in two projections (front and back), made on the same equipment: gamma camera production GE INFINIA HAW-KEYE 4. The system uses two modes of processing areas: learning mode and normal mode. In normal mode, the system classifications region of the type "normal/pathological" using pre-configured classifier. To allow operational settings of the classifier of the mode of training of the expert system. In the CAD-system, two classifiers were used, which showed better results for the anterior and posterior projections, respectively. Both classifiers are configured by the method of reference vectors without taking into account the localization of the OI and the test results have a relative frequency of correct classification 0.71 and 0.78 for the anterior and posterior projections, respectively. Results. A number of illustrative results of processing of several real scintigraphic images by means of the created CAD-system are considered. All considered examples were chosen randomly from the test and training samples. It is shown that in real medical practice excessive optimism of classifiers does not benefit the patient and can serve as the reason of undeclared pathology at diagnostics. Conclusion. Analysis of the results of CAD-system processing of scintigrams of skele-tons of real patients with visual assessment of image quality (from good to bad) did not reveal the obvious dependence of the classification results on the visual quality of images. In Gen-eral, the system has shown a good result, but for the introduction of health care institutions requires further improvement.
1 - Pacific National University.
2 - General and clinical surgery, The Far-Eastern State Medical University of Ministry of health of the Russian Federation. Khabarovsk, Russia.


 

Keywords: plane osteoscintigraphy, expert system, computer automated analysis (CAD), skeletal metastases, the object of interest (OI), the focus of hyperfixation radiopharma-ceutical (FMG RFP).

 

Corresponding author:Savin S.Z. e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Burkov S.M., Kosyh N.J., Savin S. Z., Sviridov N.M. The expert system for computer-aided analysis of osteoscintigrams with visual assessment of image quality. REJR 2018; 8 (3):227-248. DOI:10.21569/2222-7415-2018-8-3-227-248.

Received:10.06.18Accepted:06.07.18