Stratification of patients with pathology of the lymph nodes of the neck based on complex ul-trasound.

Lebedeva E.V., Zhestovskaya S.I., Narkevich A.N., Litvinova S.P.

Purpose. Evaluation of diagnostically significant signs of complex ultrasound for stratification of pa-tients with pathology of the lymph nodes (LN) of the neck in comparison with the results of morphological verification. Materials and methods. Complex ultrasonography was performed in 130 (LN n=909) patients with pathology of lymph nodes of the neck, including compression elastography (CEG) of the lymph nodes of the neck – to 39 (LN n =117)examined and 30 (LN n =180) pa-tients without diseases (control group). Morphological study confirmed malignant lesion in 32 patients, benign tumors were verified in 39 patients. Results. A comparative analysis of results B-mode, CDI and morphological study conducted of the pathology of the lymph nodes of the neck was held. The calculations of sen-sitivity and specificity of sonographic characteristics are performed. The importance of echo-graphic sings when choosing risk groups for malignant lesions of the lymph nodes of the neck was evaluated. As a result of the CEG, the reference zone was determined, qualitative and quantitative criteria of the compression elastography were evaluated. With the help of ROC-analysis the diagnostic boundary SR (ratio of stiffness coefficients) of malignant lesion of the lymph nodes was found - 4,35. Discussion. B-mode and CDI can be supplemented with compression elastography with quantitative assessment for increase the sensitivity and specificity of malignant lesions detection. It will be help to reduce the quantity of uninformative biopsies of the lymph nodes. Conclusions. The obtained results confirm that the individual ultrasound signs can't be used as an independent criterion in the assessment of malignant lymph node lesions, while it is advisable to take into account the CEG data using quantitative assessment, which is confirmed by ROC-analysis (AUC=0.965, p<0.001 - good quality model).

1 - V.F. Voino-Yasenetsky Krasnoyarsk State Medi-cal University, Krasno-yarsk, Russia 2 - Krasnoyarsk Regional Clinical Hospital, Krasnoyarsk, Russia 3 - Polyclinic No. 1 of the Administrative Depart-ment of the President of the Russian Federation, Moscow, Russia

 

Corresponding author:: Lebedeva E.V., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

For citation: Lebedeva E.V., Zhestovskaya S.I., Narkevich A.N., Litvinova S.P. Stratification of patients with pathology of the lymph nodes of the neck based on complex ultrasound. REJR 2018; 8(4):48-55. DOI:10.21569/2222-7415-2018-8-4-48-55.

Received:16.09.18Accepted:23.11.18