The value of radionuclide assessment of mechanical dyssynchrony in patients with cardiac diseases.

PET-CT as “golden standard” for early diagnosis of maxillofacial malignancies

Khabadze Z.S., Kulikova A.A., Bakaev Yu. A., Abdulkerimova S.M., Magomedov O.I., Mokhamed El-Halaf Ramiz, Mordanov O.S.

Currently the term «mechanical dyssynchrony» means a temporal heterogeneity in the activation and contractility of various parts of the heart. The principles of radionuclide methods for cardiac mechanical dyssynchrony determining differ with other visualization techniques. For scintigraphic assessment of dyssynchrony gated myocardial perfusion imaging and gated blood-pool SPECT are used. This review is dedicated to the possibilities of these methods in assessment of cardiac mechanical dyssynchrony in patients with chronic heart failure, coronary artery disease and cardiac arrhythmias. A description of a data acquisition, as well as reference figures of dyssynchrony in normal and pathological conditions are presented. Nowadays the nuclear cardiology methods are promising in the prediction to cardiac resynchronization therapy. In patients with coronary artery diseases, the presence of severe dyssynchrony on post-stress images is a sign of stunning. This symptom could be used for multivessel coronary artery lesion identification. Moreover, the presence of cardiac dyssynchrony could be useful in Wolf-Parkinson-White syndrome, arrhythmogenic right ventricular cardiomyopathy as well as ventricular arrhythmias diagnostic.


Tomsk national research medical center of

Russian academy of sciences

Tomsk, Russia


Keywords: myocardial perfusion scintigraphy, gated blood-pool SPECT, mechanical dyssynchrony, congestive heart failure, coronary artery disease, cardiac arrhythmias.

Corresponding author:  Zavadovskiy K.V., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript


For citation: Saushkin V.V., Mishkina A.I., Shipilin V.V., Zavadovsky K.V. The value of radionuclide assessment of mechanical dyssynchrony in patients with cardiac diseases. REJR 2019; 9(1):186-202. DOI:10.21569/2222-7415-2019-9-1-186-202

Received:        14.03.19 Accepted:       14.02.19