Evaluation of normal fetal lung volume and fetal lung signal intensity by magnetic-resonance imaging

Evaluation of normal fetal lung volume and fetal lung signal intensity by magnetic-resonance imaging

Syrkashev E.M., Solopova A.E., Bychenko V.G., Burov A.A., Gus A.I.

Purpose. To evaluate correlation between fetal lung signal intensity on T2WI, lung volume and gestational age and to determine reproducibility and reliability of methods.

Materials and methods. Retrospective study included 34 fetuses at gestational age from 18 to 40 weeks. First group included 23 fetuses that underwent MRI scan for pathology didn’t affect the lungs. Second group included 11 fetus with congenital diaphragmatic hernia with an unfavorable prognosis according to US.

Results. Among fetus without pulmonary hypoplasia mean value of RLSI/LSI (right lung signal intensity/liver signal intensity) was 2,348 (1,535-3,706), mean value of lung volume was 51,156 cm3 (8,99-111,48). Similar values among fetus with pulmonary hypoplasia: RLSI/LSI – 2,082 (1,393-3,130), lung volume – 15,49 cm3 (4,64-25,5). In fetuses with unaffected lungs statistical analysis revealed positive correlation between gestational age and RLSI/LSI (r=0,741, p=0,001), between gestational age and lung volume (r=0,936, p<0,001), between RLSI/LSI and lung volume (r=0,732, p=0,001). Intraclass coefficient correlation in group 1 was 0,83 and 0,81 when calculating RLSI/LSI, 0,89 and 0,85 when calculating lung volume, in group 2 – 0,80 and 0,79 when calculating RLSI/LSI, 0,87 and 0,85 when calculating lung volume.

Conclusions. Data resulting from the study allow using lung volume and ISPL/ICP in evaluation of lung maturity.

 

V.I. Kulakov National medical research center of obstetrics, gynaecology and perinatal medicine. Moscow, Russia.

 

Keywords: fetal MRI, renatal imaging, fetal lung.


Corresponding author:  Syrkashev E.M., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Syrkashev E.M., Solopova A.E., Bychenko V.G., Burov A.A., Gus A.I. Evaluation of normal fetal lung volume and fetal lung signal intensity by magnetic-resonance imaging. REJR 2019; 9(2):90-97. DOI:10.21569/2222-7415-2019-9-2-90-97.

Received:        06.04.19 Accepted:       14.06.19