The use of contrast-enhanced ultrasound in patients with pathology of the lymph nodes of the neck

Lebedeva E.V., Zhestovskaya S.I., Evdokimova E.Y., Narkevich A.N., Litvinova S.P., Shust J.А.

Purpose. To study the criteria of contrast-enhanced ultrasound in patients with pathology of the lymph nodes of the neck, in comparison with the results of morphological verification.

Materials and methods. Contrast-enhanced ultrasound (CEUS) was performed in 32 patients with pathology of the lymph nodes (LN) of the neck, followed by morphological verification.

Results and discussion. Quality indicators CEUS differ in the study of LN's neck benign and malignant lesions. The quantitative criteria turned out to be statistically significant: zero time - T0, peak of intensity - PI. Quantitative criteria were statistically significant: zero time – T0, peak intensity – PI. Malignant lesion of the neck LN is most likely to be detected when exceeding the boundary values PI=8,6 DB (Se=77,0%, Sp=92,0%), and at lower values T0=6,4 s (Se=81,0%, Sp=85,7%). Graphical representation of ROC curves of CEUS of the neck lymph nodes shows good quality of the model, the area under the curve (AUC) T0 was 0.861; PI – 0.876.

Conclusions. CEUS with qualitative and quantitative analysis may be used in the differential diagnosis in pathology of the LN's neck.

1 - V.F. Voino-Yasenetsky Krasnoyarsk State Medical University. Krasnoyarsk, Russia

2 - Krasnoyarsk Regional Clinical Hospital.

Krasnoyarsk, Russia

3 - Polyclinic No. 1 of the Administrative Department of the President of the Russian Federation. Moscow, Russia

 

 

Keywords: ultrasound, CEUS (contrast-enhanced ultrasound), ultrasound contrast agent, lymph node, metastases.

 

Corresponding author: Lebedeva E.V., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Lebedeva E.V., Zhestovskaya S.I., Evdokimova E.Y., Narkevich A.N., Litvinova S.P., Shust J.А. The use of contrast-enhanced ultrasound in patients with pathology of the lymph nodes of the neck. REJR 2019; 9(3):41-48. DOI:10.21569/2222-7415-2019-9-3- 41-48.

 

Received: 05.11.18 Accepted: 22.08.18