Shear-wave elastography and echomorphometry of uterine cervic in preterm birth prediction

Tukhbatullin M.G., Yanakova K.V.

Purpose. To determine the role of shear-wave elastography and echomorphometry of the uterine cervix in the prediction of preterm birth in pregnant women on the gestational age 16-32 weeks.

Materials and methods. From 1st of January, 2018 till 1st of January, 2019 348 pregnant women were included in the investigation on the gestational age 16-32 weeks (mean: 22.4±3.16). Mean women age was 28.44±6.28 y.o. (min-max: 17-44). On the first stage of the investigation was carried out the transvaginal ultrasound measurement of the cervical length. As a result of this measurement we determined a group of pregnant women (N=33) with high risk of preterm birth (cervical length ≤ 25mm). On the second stage in these women a Shear-Wave Elastography was carried out in order to determine cervical elasticity. We performed statistical analysis with the binary regression method and further construction of ROC (receiver operating characteristic)-curves.

Results. Mean cervical length was 26.6±2.8 mm (16-27). The pregnant women, who had preterm the cervical length was 25.3± 3.3 mm, meanwhile in the women, who delivered at term, the cervical length was 27± 2.5 mm (p<0,0001). The SWE-ratio in the women with shorter cervix and who had preterm was significantly (p<0,0001) less (0.89 ± 0.2; 0.46-1.45) than in pregnant women with short cervix who delivered at term (1.19±0.32; 0.63-2.7). While constructing ROC-curves we determined, that diagnostic performance of the transvaginal measurement of cervical length and Shear Wave Elastography is higher in the prediction of preterm birth (AUC=0.74 , p<0.0001) then in the case of cervical measurement.

Conclusion. Shear-wave elastography in combination with echomorphometry of uterine cervix is an effective tool of the prediction of preterm birth during second and third trimesters of pregnancy.

1 – Kazan State Medical Academy – Branch of Federal State Budget Educational Establishment for Complementary Professional Education “Russian Medical Academy of Continuous Professional Education” of Ministry of Health of Russia.

Kazan, Russia

2 – Municipal Clinical Hospital No.7.

Kazan, Russia

 

Keywords: Shear-wave elastography, echomorphometry of uterine cervix, preterm birth, cervical length, SWE-ratio.

 

Corresponding author:  Tukhbatullin M.G., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Tukhbatullin M.G., Yanakova K.V. Shear-wave elastography and echomorphometry of uterine cervic in preterm birth prediction. REJR 2019; 9(4):97-105. DOI:10.21569/2222-7415-2019-9-4-97-105.

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Received:        18.08.19 Accepted:       28.10.19