Computed tomography in the assessment of the efficacy of neoadjuvantchemotherapy for gastric adenocarcinoma

Computed tomography in the assessment of the efficacy of neoadjuvantchemotherapy for gastric adenocarcinoma

Silanteva N.K., Kholeva A.A., Agababian T.A., Berezovskaia T.P., Ivanov S.A.,  Kaprin A.D.,  Komin YU.A.

The literature data about the possibilities and prospects of using computed tomography to assess the therapeutic effectiveness of neoadjuvant therapy for patients with gastric cancer were analyzed.

Development of treatment methods and emergence of new imaging methods have led to the fact that currently there are various criteria for evaluating the response of the tumor. The data about the assessment and prediction of the effects of neoadjuvant therapy in patients with gastric cancer on the basis of CT-volumetry, spectral CT, CT-perfusion, and radiomic analysis are presented.

It was shown that modern methods of diagnostic imaging are powerful tool for studying the response of a malignant tumor to treatment. The potential of these methods is great, but their capabilities require a thorough in-depth study and further development of image acquisition.

1 – A. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation (A. Tsyb MRRC).

Obninsk, Russia.

2 – Military medical

facility.

Moscow, Russia.

 

Keywords: computed tomography, gastric cancer, response assesment, diagnostic imaging.

 

Corresponding author:  Agababian T.A., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Silanteva N.K., Kholeva A.A., Agababian T.A., Berezovskaia T.P., Ivanov S.A.,  Kaprin A.D.,  Komin YU.A. Computed tomography in the assessment of the efficacy of neoadjuvantchemotherapy for gastric adenocarcinoma. REJR 2019; 9(4):148-161. DOI:10.21569/2222-7415-2019-9-4-148-161.

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Received:        07.09.19 Accepted:       14.10.19