1.5T or 3T – which is best to choose for the first stage of liver iron overload evaluation in children?

1.5T or 3T – which is best to choose for the first stage of liver iron overload evaluation in children?

Nazarova E.E., Tereshchenko G.V., Kupriyanov D.A., Smetanina N.S., Novichkova G.A.

Purpose. To compare R2* values for liver iron concentration measurement at 1.5T and 3T MR scanners.

Materials and methods. 95 patients aged from 3 to 18 years with different siderosis grades were scanned on 1.5 and 3T MR scanners. For every participant liver R2* relaxometry maps were received.

Results. We established a linear relationship between liver R2* values for 1.5T and 3T MR scanners according to the 4 liver siderosis grades. The correlation coefficient in the first grade – r=0.91, in the second grade – r=0.9, in the third grade – r=0.68, in the fourth grade – r=0.93.

Conclusion. Our results demonstrated that the iron content in the liver can be assessed on both 1.5T and 3T scanners in pediatric patients with transfusional-dependent anemias.

1 - Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology.

2 - Pirogov Russian National Research Medical University.

3 - Philips Healthcare. Moscow, Russia

 

Keywords: magnetic resonance imaging (MRI), iron overload, T2 * - mapping, R2 * - mapping, magnetic resonance relaxometry.

 

Corresponding author:  Nazarova E.E., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript .

 

For citation: Nazarova E.E., Tereshchenko G.V., Kupriyanov D.A., Smetanina N.S., Novichkova G.A. 1.5T or 3T – which is best to choose for the first stage of liver iron overload evaluation in children? REJR 2020; 10(1):124-132. DOI:10.21569/2222-7415-2020-10-1-124-132.

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Received:       16.09.19 Accepted:     12.02.20