ROLE OF COMPUTED TOMOGRAPHY IN DETECTION OF VULNERABLE CORONARY PLAQUES IN COMPARISON WITH INTRAVASCULAR ULTRASOUND

Ternovoy S.K.1, Shabanova M.S.2, Gaman S.A.2, Merkulova I.N.2, Shariya M.A.1,2

1- I.M. Sechenov First Moscow State Medical University.

2- A.L. Myasnikov Institute of Clinical Cardiology of the Russian Cardiology Research Center. Moscow, Russia.

Intracoronary thrombosis is the main cause of acute coronary events.  Mechanisms of thrombosis depend on the structure of coronary plaques. Various imaging techniques have been currently developed for visualization of coronary plaque structure. Modern techniques are able to evaluate the characteristics of coronary plaques with varying degrees of specificity and sensitivity. Morphological and structural features of coronary plaques are evaluated by computed tomography. We described the "indirect" signs of instability and their combinations in the plaques detected by computed tomography in patients with acute coronary syndrome. We investigated the results of studies where the role of detection of "indirect" signs of instability in coronary plaques by computed tomography in prognosis of acute coronary events was assessed. We analyzed the studies where computed tomography and intravascular ultrasound (the reference method in the determination of morphological and structural features of the coronary plaques) were compared. We described the occurrence of "indirect" signs of instability detected by computed tomography in vulnerable plaques identified by intravascular ultrasound.

Keywords: Vulnerable plaque, coronary computed tomography, coronary CT, intravascular ultrasound, signs of plaque instability, ischemic heart disease, atherosclerosis.


 

Corresponding author:  Mariia Shabanova, Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Ternovoy S.K., Shabanova M.S., Gaman S.A., Merkulova I.N., Shariya M.A. Role of computed tomography in detection of vulnerable coronary plaques in comparison with intravascular ultrasound. REJR. 2016; 6 (3):68-79. DOI:10.21569/2222-7415-2016-6-3-68-79.

 

Received: 28.06.2016 Accepted: 12.07.2016