CT DIAGNOSTICS OF TUMOR INVASION DEPTH OF COLON CANCER: ERRORS’ANALYSIS IN CT DIAGNOSTICS OF T CATEGORY
Beketova O.G., Silanteva N.K., Mozerov S.A., Novikov N.Yu.
А. F. Tsyb Medical Radiological Research Centre. Obninsk, Russia
Purpose. To compare CT data and pathomorphological studies for identification of error cause of CT findings in assessment of the depth of tumor invasion of colon cancer.
Materials and methods. The study included 125 patients with colon cancer (49 men, 76 women, mean age 63,8±10,3 years). Computed tomography was performed on preoperative planning among all patients. The data of histological verification of the diagnosis was received before the study. Radical surgical treatment was performed on 121 patients. For statistical data processing and evaluation of CT diagnostic efficiency were calculated: the average value, deviation, standard error, operating characteristics and auxiliary criterion.
Results. CT diagnosis of the tumor and its spread along bowel walls included algorithm: visualization of the tumor, assessment of the tumor lesions symptoms, assessment of the symptoms of tumor invasion depth, definition of CT symptoms of a T category. Comprehensive analysis of discrepancy between CT findings and pathomorphological studies were performed and its reasons among 23 cases were conducted.
Conclusions. . The main causes of the false responses during CT evaluation of extraintestinal spread of colon cancer are: inflammatory and reactive changes in the surrounding tissues, peritumoral abscess and fistula, dense diligence adjacent organs and tissues to the area of the tumor lesion of the colon, malignant microinvasive in the serosa or surrounding tissues, limited opportunities in the CT in visualization of serous membrane. However high enough indicators of CT diagnostic efficiency (sensitivity 93,6%, specificity 81,5%) allow to recommend this method for the preoperative staging of colon cancer.
Keywords: multidetector computed tomography, colon cancer, TNM staging, diagnostic errors.
Corresponding author: Beketova Olga, Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript
For citation: Beketova O.G., Silanteva N.K., Mozerov S.A., Novikov N.Yu. CT diagnostics of tumor invasion depth of colon cancer: errors’ analysis in ct diagnostics of t category. REJR. 2016; 6 (4):56-67. DOI:10.21569/2222-7415-2016-6-4-56-67.
Received: 29.09.2016 Accepted: 10.10.2016